Approach to a Neonate with Cyanosis

Key points

• • Central cyanosis (tongue and mucous membranes) is always abnormal and needs urgent assessment.
• • The hyperoxia test helps: little rise in oxygen with 100% suggests cyanotic congenital heart disease.
• • Cyanotic heart lesions (the 5 Ts): Transposition, Tetralogy, Truncus, Total anomalous venous return, Tricuspid atresia.
• • Duct-dependent lesions may need prostaglandin to keep the duct open.