🧠 Nervous System🟢 BasicDemyelinating Diseases

Multiple Sclerosis

A disease in which the immune system attacks the insulating sheath of nerves in the brain and spinal cord, causing scattered neurological problems.

Key points

Multiple sclerosis is an autoimmune disease that destroys the myelin sheath of nerves in the brain and spinal cord.
The damage is scattered in place and in time, so different parts of the nervous system are affected at different times.
Common features include blurred or double vision, weakness, numbness, unsteadiness and bladder problems.
The commonest pattern is relapsing-remitting, with attacks followed by partial or full recovery, which may later become progressive.
It is supported by MRI showing scattered plaques and by finding certain proteins (oligoclonal bands) in the spinal fluid.

Memory trick

Multiple sclerosis is autoimmune loss of myelin in the brain and cord, scattered in place and time: vision, weakness, numbness, unsteadiness, bladder; relapsing-remitting commonest; MRI plaques plus oligoclonal bands in the CSF.

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🧠 Nervous System🟢 BasicDemyelinating Diseases

Multiple Sclerosis

A disease in which the immune system attacks the insulating sheath of nerves in the brain and spinal cord, causing scattered neurological problems.

Key points

Multiple sclerosis is an autoimmune disease that destroys the myelin sheath of nerves in the brain and spinal cord.
The damage is scattered in place and in time, so different parts of the nervous system are affected at different times.
Common features include blurred or double vision, weakness, numbness, unsteadiness and bladder problems.
The commonest pattern is relapsing-remitting, with attacks followed by partial or full recovery, which may later become progressive.
It is supported by MRI showing scattered plaques and by finding certain proteins (oligoclonal bands) in the spinal fluid.

Memory trick

All of General Medicine More Nervous System