🦠 Microbiology & Infectious Disease🟢 BasicRabies and Lyssaviruses

Rabies

A near-universally fatal viral encephalitis transmitted by animal bites.

Key points

Rhabdovirus in saliva; travels along nerves to the brain (Negri bodies on histology).
Hydrophobia, aerophobia and agitation (furious form) or paralysis (dumb form).
Post-exposure prophylaxis includes immediate wound washing and, when indicated, rabies vaccine and rabies immunoglobulin according to exposure category and local or national guidelines.
Fully preventable with timely prophylaxis; almost always fatal once symptomatic.

Rabies: wash the wound at once, give the vaccine, and add immunoglobulin when the exposure category indicates it.

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🦠 Microbiology & Infectious Disease🟢 BasicRabies and Lyssaviruses

A near-universally fatal viral encephalitis transmitted by animal bites.

Rhabdovirus in saliva; travels along nerves to the brain (Negri bodies on histology).
Hydrophobia, aerophobia and agitation (furious form) or paralysis (dumb form).
Post-exposure prophylaxis includes immediate wound washing and, when indicated, rabies vaccine and rabies immunoglobulin according to exposure category and local or national guidelines.
Fully preventable with timely prophylaxis; almost always fatal once symptomatic.

Rabies: wash the wound at once, give the vaccine, and add immunoglobulin when the exposure category indicates it.