🧬 Reproductive🟢 BasicTestis

Testicular Tumours

Cancers of the testis, the commonest solid cancer in young men, which usually present as a painless lump.

Key points

Most testicular tumours arise from the germ cells and are divided into seminomas and non-seminomas.
They usually present as a painless, firm swelling of the testis in a young or middle-aged man.
Seminomas grow more slowly and are very sensitive to radiation, while the non-seminomas include more varied and faster types.
Blood tumour markers help: alpha-fetoprotein and beta-hCG are raised in many non-seminomas, and LDH reflects the bulk of the tumour.
They spread first to the lymph nodes at the back of the abdomen, following the testis's original blood supply.

Memory trick

Testicular tumours are mostly germ-cell (seminoma versus non-seminoma), a painless firm testis lump in a young man; markers AFP and beta-hCG (non-seminoma) and LDH for bulk; they spread to the para-aortic nodes.

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🧬 Reproductive🟢 BasicTestis

Testicular Tumours

Cancers of the testis, the commonest solid cancer in young men, which usually present as a painless lump.

Key points

Most testicular tumours arise from the germ cells and are divided into seminomas and non-seminomas.
They usually present as a painless, firm swelling of the testis in a young or middle-aged man.
Seminomas grow more slowly and are very sensitive to radiation, while the non-seminomas include more varied and faster types.
Blood tumour markers help: alpha-fetoprotein and beta-hCG are raised in many non-seminomas, and LDH reflects the bulk of the tumour.
They spread first to the lymph nodes at the back of the abdomen, following the testis's original blood supply.

Memory trick

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