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Also known as: nephrosis · heavy proteinuria
The triad of heavy proteinuria (>3.5 g/day), hypoalbuminaemia and oedema, usually with hyperlipidaemia. In children it is most often minimal-change disease and steroid-responsive.
Children (minimal-change disease) and adults (focal segmental glomerulosclerosis, membranous nephropathy, diabetic nephropathy, amyloid, lupus and infection-related disease).
Idiopathic nephrotic syndrome (esp. children — minimal change)
Caution: Monitor for steroid effects; distinguish steroid-sensitive from steroid-resistant disease.
Reduce proteinuria and control oedema/lipids
Caution: Monitor renal function and potassium with ACEi/ARB.
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🚩 Report outdated / suggest update