First principle: a preventable cancer — two intervention points
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Vaccination — prevents, does not treat
- Routine at ~11–12 years (from 9; catch‑up into the twenties).
- 🚩 The vaccine prevents new HPV infection but does not treat existing infection or established CIN/cancer.
- Vaccinated people still require screening (not all oncogenic types are covered).
Screening — the modern shift
From abnormal screen to diagnosis
Pitfalls
- Believing vaccination removes the need to screen.
- Expecting the vaccine to clear an existing infection.
- Memorising one country's Pap schedule as universal.
Pearls
- 🎯 Vaccinate (prevents) + screen (HPV‑based); abnormal screen → colposcopy → biopsy.
- 🩺 Offer the vaccine even to the already‑sexually‑active within the eligible age — it still protects against not‑yet‑acquired types.
Next → The quietest cancer begins with a lump (Concept 40).