Part 1 · Cardiovascular Medicine
Same concept, other depth: Foundation →
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| Cell | Phase 0 (upstroke) | Plateau | Automaticity | Drug linkage |
|---|---|---|---|---|
| SA / AV nodal | slow Ca²⁺ influx | no true phase‑2 plateau | phase‑4 "funny" current (Iƒ) + Ca²⁺ currents | beta blockers slow phase 4; verapamil/diltiazem slow AV conduction |
| Atrial / ventricular / Purkinje | fast Na⁺ influx | phase 2: Ca²⁺ in balanced by K⁺ out | normally low | Na‑channel blockers act on phase 0; K‑channel blockers prolong repolarisation |
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