The simple idea
TRH from the hypothalamus tells the pituitary to release TSH. TSH tells the thyroid to make mostly T4 and some T3. T4 is converted in tissues to active T3, and free hormone feeds back to lower TSH.
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Part 7 · Hormones II — Sugar, Calcium, Potassium and Thyroid
Same concept, other depth: Clinical Reasoning →
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TRH from the hypothalamus tells the pituitary to release TSH. TSH tells the thyroid to make mostly T4 and some T3. T4 is converted in tissues to active T3, and free hormone feeds back to lower TSH.
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