Part 8 · Endocrine Physiology
Same concept, other depth: Foundation →
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Plasma calcium (total ~2.2–2.6 mmol/L; 8.5–10.5 mg/dL): ~50% ionised (1.15–1.35 mmol/L), ~40% protein‑bound (albumin), ~10% complexed. Alkalosis increases albumin binding → ↓ ionised Ca²⁺ (tetany with hyperventilation). Corrected calcium (mg/dL) ≈ total + 0.8 × (4.0 − albumin g/dL) — an estimate; measure ionised Ca²⁺ when it matters.
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