Part 2 · Contrast Media, Nuclear Medicine and Radiotherapy

20. Renal and Cardiac Nuclear Imaging

~3 min read

Same concept, other depth: Foundation →

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Tracer	Handling	Study	Key indications
Tc‑99m DMSA	binds proximal tubular cells (cortex)	static	cortical scarring (pyelonephritis, VUR), differential (split) function, ectopic/horseshoe kidney, acute pyelonephritis (cold areas)
Tc‑99m DTPA	glomerular filtration only	dynamic	GFR measurement, renogram; also aerosol ventilation
Tc‑99m MAG3	tubular secretion (high extraction)	dynamic	obstruction (diuretic renogram), neonates and poor function, transplant (ATN vs rejection vs leak)
Captopril renography	ACE inhibition removes efferent tone in a stenotic kidney	DTPA/MAG3 before and after captopril	renovascular hypertension (largely superseded)

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Tracer

Handling

Study

Key indications

Tc‑99m DMSA

binds proximal tubular cells (cortex)

static

cortical scarring (pyelonephritis, VUR), differential (split) function, ectopic/horseshoe kidney, acute pyelonephritis (cold areas)

Tc‑99m DTPA

glomerular filtration only

dynamic

GFR measurement, renogram; also aerosol ventilation

Tc‑99m MAG3

tubular secretion (high extraction)

dynamic

obstruction (diuretic renogram), neonates and poor function, transplant (ATN vs rejection vs leak)

Captopril renography

ACE inhibition removes efferent tone in a stenotic kidney

DTPA/MAG3 before and after captopril

renovascular hypertension (largely superseded)