Part 9 · Haematology
Same concept, other depth: Foundation →
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AML is a clonal myeloid neoplasm with impaired differentiation. It presents through marrow failure: anaemia, infection, bleeding, bruising, mucosal bleeding, and sometimes tissue infiltration such as gingival or skin disease. Diagnosis integrates smear, flow, marrow and genetics; some genetic AML entities no longer need a simple 20 percent blast rule.
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