The reasoning: plasma proteins set oncotic pressure, transport and defence
Blood volume ≈ 70 mL/kg (men) and 65 mL/kg (women); haematocrit ≈ 40–52% in men and 36–47% in women (laboratory dependent). Total plasma protein ≈ 6.0–8.0 g/dL: albumin 3.5–5.0 g/dL (liver; half‑life ≈ 20 days; ~75–80% of plasma oncotic pressure ≈ 25 mmHg), globulins (α₁: α₁‑antitrypsin; α₂: haptoglobin, ceruloplasmin, α₂‑macroglobulin; β: transferrin, C3, LDL; γ: immunoglobulins) and fibrinogen 200–400 mg/dL.