Part 4 · Gastrointestinal Physiology
Same concept, other depth: Foundation →
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Acini produce a near‑isotonic primary fluid (basolateral NKCC1 loads Cl⁻; Ca²⁺‑activated apical Cl⁻ channels; Na⁺ and water follow). Ducts, relatively water‑impermeable, reabsorb Na⁺ and Cl⁻ and secrete K⁺ and HCO₃⁻ — so final saliva is hypotonic, and its composition depends on flow.
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